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Khvatova EM, Rubanova NA, Prudchenko IA, Mikhailova II

reported that sulforaphane exerted a neuroprotective effect in a 6-OHDA-induced acute mouse model and attributed it to the ability of sulforaphane to enhance glutathione levels and its dependent enzymes, to up-regulate Nrf2 and to modulate the ERK1/2 pathway in the brain 28

Bermans approach is built around this philosophy

69 This process requires the ex vivo expansion of autologous cells and implantation into the degenerated disc

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